Reviews and Guidelines

Guidelines for the management of asthma in adults and adolescents: Position statement of the South African Thoracic Society – 2021 update

U G Lalloo, I S Kalla, S Abdool-Gaffar, K U Dheda, C F N Koegelenberg, M Greenblatt, C Feldman, M L Wong, R N van Zyl-Smit

Abstract


Summary

Asthma prevalence is increasing worldwide, and surveys indicate that most patients in developed and developing countries, including South Africa, do not receive optimal care and are therefore not well controlled. Standard management guidelines adapted to in-country realities are important to support optimal care. The South African Thoracic Society (SATS) first published a guideline for the management of chronic persistent asthma in 1992, which has subsequently been revised several times. The main aim of the present document was to revise and update SATS’ statement on the suggested management of chronic asthma, based on the need to promote optimal care and control of asthma, together with the incorporation of new concepts and drug developments. This revised document reinforces optimal care and incorporates the following primary objectives to achieve the recent advances in asthma care: • continued emphasis on the use of inhaled corticosteroids (ICS) as the foundation of asthma treatment • to reduce the reliance on short-acting beta-2 agonist (SABA) monotherapy for asthma symptoms • to incorporate the evidence and strategy for the use of the combination of an ICS and formoterol for acute symptom relief (instead of a SABA) • to incorporate the evidence and strategy for the use of as-needed ICS-long-acting beta agonists (LABA) for patients with infrequent symptoms or ‘mild’ asthma • to incorporate the evidence and strategy for the use of a long-acting muscarinic antagonist (LAMA) in combination with ICS-LABA; and • to incorporate the evidence and strategy for the use of and management with a biologic therapy in severe asthma


Authors' affiliations

U G Lalloo, Life Mount Edgecombe Hospital, Durban, South Africa

I S Kalla, Division of Pulmonology, Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

S Abdool-Gaffar, Kingsway Hospital, Amanzimtoti, South Africa

K U Dheda, Centre for Lung Infection and Immunity,Division of Pulmonology, Department of Medicine and UCT Lung Institute and South African Medical Research Council/UCT Centre for the Study of Antimicrobial Resistance, University of Cape Town, South Africa

C F N Koegelenberg, Faculty of Infectious and Tropical Diseases, Department of Immunology and Infection, London School of Hygiene and Tropical Medicine,United Kingdom; and Division of Pulmonology, Department of Medicine, Stellenbosch University, Cape Town, South Africa

M Greenblatt, Milpark Hospital, Johannesburg, South Africa

C Feldman, Division of Pulmonology, Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

M L Wong, Division of Pulmonology, Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

R N van Zyl-Smit, Centre for Lung Infection and Immunity,Division of Pulmonology, Department of Medicine and UCT Lung Institute and South African Medical Research Council/UCT Centre for the Study of Antimicrobial Resistance, University of Cape Town, South Africa

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Cite this article

African Journal of Thoracic and Critical Care Medicine 2021;27(4):171.

Article History

Date submitted: 2021-12-24
Date published: 2022-02-01

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African Journal of Thoracic and Critical Care Medicine| Online ISSN: 2617-0205

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